Morpheus study

Research protocol

Protocol summary:

For patients with curable and operable rectal cancer, it has been shown that patients who had a complete response (tumor disappearing) after standard chemoradiation treatments could avoid or delay surgery safely.

This study is exploring two non-operative treatment strategies using dose escalation either with external beam radiation (Arm A) or targeted endorectal brachytherapy (Arm B). Patients are randomly assigned to either arm A or Arm B.

For both arms, after treatment, if the tumor disappears, there is no surgery. If the tumour is still present, standard surgery will be done.
The objectives are to evaluate which of the two strategies is best to achieve the highest rate of tumour disappearance allowing for a non-surgical cure.

For more information, please contact:

Alix Legrand – Clinical Research Associate  

T: 514-340-8222 ext. 28443 


Aubrée Brodin – Clinical Research Associate 


T: 514-340-8222 ext. 26199 

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