Day 3: Clinical Trials Updates and Challenges: Time for Discussion Planned Watch and Wait Dose Escalation Contact Therapy (OPERA) results - Dr. Jean-Pierre Gérard High Dose Rate Endorectal Brachytherapy (Morpheus study) - Dr. Te Vuong Consolidation Chemotherapy updates (OPRA study) - Dr. Julio Garcia Aguliar Total neoadjuvant treatment: induction chemotherapy (Prodige 23) - Dr. Véronique Vendrely Introduction and Summary